Janney is a surname. Notable people with the surname include:
Allison Janney (born 1959), American actress
Christopher Janney (born 1950), American interactive sound and light artist
Craig Janney (born 1967), American retired hockey player
Ernest Lloyd Janney (1893–1941), Canadian military pilot
Eli H. Janney (1831–1912), American inventor
Eli Janney (musician), American record producer and musician
Jack R. Janney (1924–2006), American structural engineer and innovator in the understanding of structural collapses
Stuart S. Janney, Jr. (1907–1988), American attorney, leading horse breeder
Barbara Phipps Janney (1911–1987), member of the American horse racing Phipps family
Stuart Symington Janney III (born 1948), American investment banker, racehorse owner