James Bruce (1730–1794) was a Scottish traveller and travel writer.
James Bruce may also refer to:
James Bruce (bishop) (died 1447), Bishop of Dunkeld, Chancellor of Scotland and Bishop of Glasgow
James Bruce (comptroller) (c.1670 – c.1732), Member of Parliament for Marlborough and joint comptroller of British Army accounts
James Bruce (Chief Justice) (1691–1749), Chief Justice of Barbados
Jacob Bruce (1669–1735), or James Bruce, Russian field-marshal, founder of the Russian branch of the Scottish family
James Bruce (1732–1791), Governor general of Saint Petersburg and last male member of the Russian branch
James Bruce, 8th Earl of Elgin (1811–1863), Anglo-Scottish diplomat
James Andrew Thomas Bruce (1846–1921), Royal Navy admiral
James Bruce (English cricketer) (born 1979), English cricketer
James Bruce (Zimbabwean cricketer) (born 1993), Zimbabwean cricketer
James Bruce (1769–1798), Member of Parliament for Marlborough
James E. Bruce (1927–2008), politician in the American state of Kentucky