Jaffe is a surname. It may also be spelled Jaffé:
Aaron Jaffe. American politicianAndrew Jaffe, journalistAniela Jaffé, (February 20, 1903 – October 30, 1991), a Swiss analyst who for many years was a co-worker of Carl JungArthur Jaffe, mathematical physicistBilly Jaffe (born 1969), color analyst for the New York Islanders on MSG PlusCharles Jaffe (circa 1879 – 12 July 1941), Belarusian-American chess masterDaniel Jaffe, American astronomerDavid Jaffe, video game designer and directorDavid A. Jaffe, composer of contemporary classical and electronic/computer musicElaine Jaffe, American pathologist, expert in hematopathologyEliezer Jaffe, professorFrederick S. Jaffe, (1925–1978), vice president of Planned Parenthood and founder of the Guttmacher InstituteJerome H. Jaffe, psychiatristMarielle Jaffe (born 1989), an American model and actressMichael Jaffé (3 June 1923 – 13 July 1997), a British art historian and curatorMoe Jaffe (1901–1972), American songwriter and band leaderNaomi Jaffe, activistNicole Jaffe, American actressNorman Jaffe, American architectSir Otto Jaffe (born 1846), prominent Jewish businessman, High Sheriff and Lord Mayor of BelfastPeter Jaffe (born 1913), British sailor and Olympic silver medalistPhilipp Jaffé (February 17, 1819 – April 3, 1870), a German historian and philologistPhilip Jaffe (1895–1980), left-wing American editor and writer.Robert Jaffe, physicist and professorRobert Jaffe (stockbroker) (born 1944), associate of Bernard MadoffRona Jaffe (born 1932), U.S. authorSam Jaffe (actor) (1891–1984), American film actorSam Jaffe (producer) (1901–2000), American film producer later in EnglandSarah Jaffe (born 1986), American singer-songwriterScott Jaffe (born 1969), American freestyle swimmerStanley R. Jaffe (born 1940), American film producerStephen Jaffe, American composerTaliesin Jaffe, (born 1977), American voice actorTheodor Julius Jaffé (August 17, 1823 – April 11, 1898), a German actorWerner Jaffé (October 27, 1914 – May 3, 2009), a German chemist and university professorWilliam Jaffé (1898 – 1980), an American economist and historian of economic thought