CAS Number 210179-46-7 ChemSpider 8722599 Formula C25H25NO2 | PubChem CID 10547208 ECHA InfoCard 100.230.181 Molar mass 371.47 g/mol | |
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Legal status CA: Schedule IIDE: Anlage II (Prohibited)US: Schedule II-N (Poland) | ||
JWH-081 is an analgesic chemical from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. With a Ki of 1.2nM it is fairly selective for the CB1 subtype, its affinity at this subtype approximately 10x the affinity at CB2. It was discovered by and named after Dr. John W. Huffman.
JWH-081 may be neurotoxic to animals when administered in high doses.
Legal Status
As of October 2015 JWH-081 is a controlled substance in China.
References
JWH-081 Wikipedia(Text) CC BY-SA