Supriya Ghosh (Editor)

Isopropyl chloride

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Formula
  
C3H7Cl

Appearance
  
Colourless liquid

Density
  
862 kg/m³

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Isopropyl chloride (also chlorodimethylmethane, 2-propyl chloride, sec-propyl chloride or 2-chloropropane) is a colorless, flammable chemical compound . It has the chemical formula C3H7Cl and is prepared by refluxing isopropyl alcohol with concentrated hydrochloric acid and zinc chloride.

Structurally, isopropyl chloride is an organochlorine compound as well as a secondary (2°) haloalkane, the latter designation identifying the two C-C bonds seen around the carbon atom covalently bonded with the chlorine substituent. To compare, its structural isomer, 1-chloropropane, is instead an example of a primary (1°) haloalkane, as the chlorine-bound carbon atom has only one C-C bond.

As a laboratory reactant, heating 2-chloropropane with alcoholic potassium hydroxide will yield propene (an alkene) by a dehydrohalogenation reaction. However, reacting with potassium hydroxide would compete with an SN2 nucleophilic substitution reaction (minor product) because OH-ion is a strong, sterically unhindered nucleophile. Because of this, potassium tert-butoxide is one example of a better reagent to use.

References

Isopropyl chloride Wikipedia