EC number 5.3.3.2 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 9033-27-6 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, an isopentenyl-diphosphate Delta-isomerase (EC 5.3.3.2, see also: Isopentenyl Pyrophosphate) is an enzyme that catalyzes the chemical reaction
isopentenyl diphosphateHence, this enzyme has one substrate, isopentenyl diphosphate, and one product, dimethylallyl diphosphate.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is isopentenyl-diphosphate Delta3-Delta2-isomerase. Other names in common use include isopentenylpyrophosphate Delta-isomerase, methylbutenylpyrophosphate isomerase, and isopentenylpyrophosphate isomerase. This enzyme participates in biosynthesis of steroids and terpenoid biosynthesis.
Structural studies
As of late 2007, 25 structures have been solved for this class of enzymes, with PDB accession codes 1HX3, 1HZT, 1I9A, 1NFS, 1NFZ, 1OW2, 1P0K, 1P0N, 1PPV, 1PPW, 1PVF, 1Q54, 1R67, 1VCF, 1VCG, 1X83, 1X84, 2B2K, 2DHO, 2G73, 2G74, 2I6K, 2ICJ, 2ICK, and 2PNY.