Samiksha Jaiswal (Editor)

Isoflavonoid synthase

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EC number
  
1.14.13.136

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

2-hydroxyisoflavanone synthase (EC 1.14.13.136, CYT93C, IFS, isoflavonoid synthase) is an enzyme with systematic name liquiritigenin,NADPH:oxygen oxidoreductase (hydroxylating, aryl migration). This enzyme catalyses the following chemical reactions:

liquiritigenin + O2 + NADPH + H+ ⇌ 2,4',7-trihydroxyisoflavanone + H2O + NADP+

and

(2S)-naringenin + O2 + NADPH + H+ ⇌ 2,4',5,7-tetrahydroxyisoflavanone + H2O + NADP+

Isoflavonoid synthase requires cytochrome P450.

References

Isoflavonoid synthase Wikipedia
(Text) CC BY-SA


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