Harman Patil (Editor)

International Prognostic Scoring System

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The International Prognostic Scoring System (IPSS) is used by many doctors to help assess the severity of a patient's myelodysplastic syndrome (MDS). Based on the IPSS score, the patient's history, and his/her personal observations, the physician will design a treatment plan to address the MDS.

The IPSS uses three "prognostic indicators" to develop a "score" which may be useful in understanding how the MDS may progress:

  • the proportion of blast cells in the marrow
  • the type of chromosomal changes, if any, in the marrow cells
  • the presence of one or more low blood cell counts (cytopenias)
  • Each indicator is rated according to its severity and the ratings are combined into a "score."

    Scores are sorted into one of four risk categories:

  • low
  • intermediate-1
  • intermediate-2
  • high
  • The two lower categories can be further described as the lower risk group while the two upper categories can be further described as the higher risk group.

    References

    International Prognostic Scoring System Wikipedia