Species Human Entrez 282618 | Human Mouse Ensembl ENSG00000182393 | |
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Aliases IFNL1, IL-29, IL29, interferon, lambda 1, interferon lambda 1 External IDs OMIM: 607403 HomoloGene: 131189 GeneCards: IFNL1 |
Interleukin-29 (IL-29) is a protein that in humans is encoded by the IL29 gene that resides on chromosome 19.
IL-29 is a member of the helical cytokine family and is a type III interferon. It is also known as IFNλ1 and is highly similar in amino acid sequence to the IL-28, the other type III interferon. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL29 is not present in the mouse genome.
References
Interleukin 29 Wikipedia(Text) CC BY-SA