Inositol 2 dehydrogenase

In enzymology, an inositol 2-dehydrogenase (EC 1.1.1.18) is an enzyme that catalyzes the chemical reaction

myo-inositol + NAD⁺ ⇌ 2,4,6/3,5-pentahydroxycyclohexanone + NADH + H⁺

Thus, the two substrates of this enzyme are myo-inositol and NAD⁺, whereas its 3 products are 2,4,6/3,5-pentahydroxycyclohexanone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is myo-inositol:NAD⁺ 2-oxidoreductase. Other names in common use include myo-inositol 2-dehydrogenase, myo-inositol:NAD⁺ oxidoreductase, inositol dehydrogenase, and myo-inositol dehydrogenase. This enzyme participates in inositol metabolism and inositol phosphate metabolism.