Kalpana Kalpana (Editor)

Inosine monophosphate synthase

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Species
  
Human

Entrez
  
471

Human
  
Mouse

Ensembl
  
ENSG00000138363

Inosine monophosphate synthase

Aliases
  
ATIC, AICAR, AICARFT, HEL-S-70p, IMPCHASE, PURH, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

External IDs
  
OMIM: 601731 MGI: 1351352 HomoloGene: 2983 GeneCards: ATIC

Bifunctional purine biosynthesis protein PURH is a protein that in humans is encoded by the ATIC gene.

ATIC encodes an enzyme which generates inosine monophosphate from aminoimidazole carboxamide ribonucleotide.

It has two functions:

  • EC 2.1.2.3 - 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase
  • EC 3.5.4.10 - IMP cyclohydrolase
  • References

    Inosine monophosphate synthase Wikipedia