Girish Mahajan (Editor)

Influenza non structural protein

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Symbol
  
Flu_NS1

InterPro
  
IPR000256

PDB
  
RCSB PDB; PDBe; PDBj

Pfam
  
PF00600

Pfam
  
structures

PDBsum
  
structure summary

Influenza non-structural protein (NS1) is a homodimeric RNA-binding protein found in influenza virus that is required for viral replication. NS1 binds polyA tails of mRNA keeping them in the nucleus. NS1 inhibits pre-mRNA splicing by tightly binding to a specific stem-bulge of U6 snRNA.

References

Influenza non-structural protein Wikipedia