EC number 4.1.1.74 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 9074-92-4 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, an indolepyruvate decarboxylase (EC 4.1.1.74) is an enzyme that catalyzes the chemical reaction
3-(indol-3-yl)pyruvateHence, this enzyme has one substrate, 3-(indol-3-yl)pyruvate, and two products, 2-(indol-3-yl)acetaldehyde and CO2.
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming]. Other names in common use include indol-3-yl-pyruvate carboxy-lyase, and 3-(indol-3-yl)pyruvate carboxy-lyase. This enzyme participates in tryptophan metabolism.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1OVM.
References
Indolepyruvate decarboxylase Wikipedia(Text) CC BY-SA