Indole 3 acetaldehyde reductase (NADH)

In enzymology, an indole-3-acetaldehyde reductase (NADH) (EC 1.1.1.190) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are (indol-3-yl)ethanol and NAD⁺, whereas its 3 products are (indol-3-yl)acetaldehyde, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is (indol-3-yl)ethanol:NAD⁺ oxidoreductase. Other names in common use include indoleacetaldehyde reductase, indole-3-acetaldehyde reductase (NADH), and indole-3-ethanol:NAD⁺ oxidoreductase. This enzyme participates in tryptophan metabolism.