Iles is a surname. Notable people with the surname include:
Albert Iles (1914–1979), English footballerAlex Iles, American musicianAndy Iles (born 1992), American ice hockey playerBob Iles (born 1955), English footballerBradley Iles (born 1983), New Zealand golferBrian Iles, American animation writerEdna Iles (1905–2003), English classical pianistElijah Iles (1796-1883), American pioneer and businessmanFrancis Iles (1893-1971), English crime writer (real name: Anthony Berkeley Cox)Greg Iles (born 1960), American writerJames Iles (born 1990), English cricketerJon Iles (born 1954), English actorNikki Iles (born 1963), English musicianRay K Iles, British scientistRichard Iles (born 1962), English musicianSalim Iles (born 1975), Algerian swimmerSam Iles (born 1987), Australian rules footballer