Puneet Varma (Editor)

Idarucizumab

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Type
  
Fab fragment

Target
  
Dabigatran

ATC code
  
V03AB37 (WHO)

Source
  
Humanized (from mouse)

Trade names
  
Praxbind

CAS Number
  
1362509-93-0

Idarucizumab 182922305082drugbiologyPB0269Idarucizumab

How to pronounce idarucizumab praxbind memorizing pharmacology extended explanation


Idarucizumab, sold under the brand name Praxbind, is a monoclonal antibody designed for the reversal of anticoagulant effects of dabigatran.

This drug was developed by Boehringer Ingelheim Pharmaceuticals. A large study sponsored by the manufacturer found that idarucizumab effectively reversed anticoagulation by dabigatran within minutes. It was FDA approved in October 2015. In the United States the wholesale cost is $3500 US.

References

Idarucizumab Wikipedia