The icon of Saints John the Baptist and Minias is an early-Quattrocento (1400–1450) wood panel with tempera painting by the Florentine painter Bicci di Lorenzo (1373–1452).
Icon of Saints John the Baptist and Minias (Bicci di Lorenzo) Wikipedia
Saint Minias of Florence is also known as San Miniato. The painting is tempera and gold sheet on poplar. It currently resides in the Legion of Honor Museum in San Francisco, California, which also has a similar peaked wood panel by Bicci, depicting Saints Anthony and Stephen. These are almost certainly panels from a larger altarpiece.