Species Human Entrez 80895 | Human Mouse Ensembl ENSG00000132323 | |
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Aliases ILKAP, ILKAP2, ILKAP3, PP2C-DELTA, PPM1O, ILK associated serine/threonine phosphatase External IDs MGI: 1914694 HomoloGene: 31525 GeneCards: ILKAP | ||
Integrin-linked kinase-associated serine/threonine phosphatase 2C is an enzyme that in humans is encoded by the ILKAP gene.
The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.
Interactions
ILKAP has been shown to interact with Integrin-linked kinase.
References
ILKAP Wikipedia(Text) CC BY-SA