Species Human Entrez 10437 | Human Mouse Ensembl ENSG00000216490 | |
Aliases IFI30, GILT, IFI-30, IP30, IP-30, lysosomal thiol reductase External IDs MGI: 2137648 HomoloGene: 38171 GeneCards: IFI30 | ||
Gamma-interferon-inducible lysosomal thiol reductase is an enzyme that in humans is encoded by the IFI30 gene.
The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing.
References
IFI30 Wikipedia(Text) CC BY-SA