EC number 1.14.11.29 BRENDA BRENDA entry KEGG KEGG entry | IntEnz IntEnz view ExPASy NiceZyme view MetaCyc | |
Hypoxia-inducible factor-proline dioxygenase (EC 1.14.11.29, HIF hydroxylase) is an enzyme with systematic name hypoxia-inducible factor-L-proline, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating). This enzyme catalyses the following chemical reaction
hypoxia-inducible factor-L-proline + 2-oxoglutarate + O2Hypoxia-inducible factor-proline dioxygenase contains iron, and requires ascorbate.
References
Hypoxia-inducible factor-proline dioxygenase Wikipedia(Text) CC BY-SA