Rahul Sharma (Editor)

Hypertrophic decidual vasculopathy

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Hypertrophic decidual vasculopathy

In pathology, hypertrophic decidual vasculopathy, abbreviated HDV, is the histomorphologic correlate of gestational hypertension, as may be seen in intrauterine growth restriction (IUGR) and HELLP syndrome.

The name of the condition describes its appearance under the microscope; the smooth muscle of the decidual (or maternal) blood vessels is hypertrophic, i.e. the muscle part of the blood vessels feeding the placenta is larger due to cellular enlargement.

Morphologic features

The morphologic features of mild and moderate HDV include:

  • Perivascular inflammatory cells,
  • +/-Vascular thrombosis,
  • Smooth muscle hypertrophy, and
  • Endothelial hyperplasia.

    • Severe HDV is characterized by:

  • Atherosis - foamy macrophages within vascular wall, and
  • Fibrinoid necrosis of vessel wall (amorphous eosinophilic vessel wall).

    • References

    Hypertrophic decidual vasculopathy Wikipedia
    (Text) CC BY-SA