EC number 1.12.1.3 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 9027-05-8 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a hydrogen dehydrogenase (NADP+) (EC 1.12.1.3) is an enzyme that catalyzes the chemical reaction
H2 + NADP+
Thus, the two substrates of this enzyme are H2 and NADP+, whereas its two products are H+ and NADPH.
This enzyme belongs to the family of oxidoreductases, specifically those acting on hydrogen as donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is hydrogen:NADP+ oxidoreductase. Other names in common use include NADP+-linked hydrogenase, NADP+-reducing hydrogenase, hydrogen dehydrogenase (NADP+), and simply hydrogenase (which is ambiguous).
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2AUV.
References
Hydrogen dehydrogenase (NADP+) Wikipedia(Text) CC BY-SA