Houle is a surname. Notable people with the surname include:
David Houle (21st century), evolutionary biologist
Eric Houle (born 1981), Arena Football League kicker
Marie-Josée Houle (21st century), Canadian accordionist
Marielle Houle (21st century), Canadian criminal
Mariette Houle (born 1954), former Canadian handball player
Martin Houle (born 1985), Canadian professional ice hockey player
Réjean Houle (born 1949), Canadian ice hockey forward