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Houben-Weyl Methods of Organic Chemistry, established in 1909 by the German chemist Theodor Weyl, is a classic chemistry text. It consisted initially of two volumes and covered literature published as early as 1834. Heinrich J. Houben revised and reissued it in 1913. It is considered one of the most significant resources for chemists.
The 4th edition was the last one published in German. It was published by Thieme from 1952 to 1987, with supplementary volumes published between 1982 and 1999. It consists of 16 volumes, some of which are further divided, giving 70 individual tomes.
A new English-language edition was published by Thieme from 2000 to 2010 as Science of Synthesis in 48 volumes. It is constantly updated.
References
Houben-Weyl Methods of Organic Chemistry Wikipedia(Text) CC BY-SA