Hotchkiss is a surname. Notable people with the surname include:
Avis Hotchkiss, early American motorcycle traveler with her daughter EffieBenjamin B. Hotchkiss (1826–1885), 19th-century American engineerEffie Hotchkiss, pioneering American motorcyclist with her mother AvisGiles W. Hotchkiss (1815–1878), American politicianHarley Hotchkiss (1927–2011), Canadian businessmanHerman Hotchkiss (1765–1836), American settlerJedediah Hotchkiss (1828–1899), cartographer for the Confederate Army during the American Civil WarJulius Hotchkiss (1810–1878), American politicianL. D. Hotchkiss (1893–1964), American journalistMaria Bissell Hotchkiss (1827–1901), wife of Benjamin B. Hotchkiss and founder of The Hotchkiss School and Hotchkiss LibraryMerritt Hotchkiss, Canadian politicianRalf Hotchkiss, American inventorRollin Hotchkiss (1911–2004), American biochemistSylvester Hotchkiss, American architectWilliam Horace Hotchkiss (1864–?), American writerWilliam O. Hotchkiss (1878–1954), American geologistWilliam Hotchkiss III (born 1943), former commanding general of the Philippine Air Force