Horne is a surname. Notable people with the surname include:
Alistair Horne (born 1925), British historianBarry Horne (1952–2001), British animal-rights activistBarry Horne (footballer) (born 1962), Welsh footballerCharles Silvester Horne (1865–1914), British minister and politicianDes Horne (born 1939), South African and English footballerDonald Horne (1921–2005), Australian writer and social criticEdmond Henry Horne (1864–1953), Canadian prospectorEdward Horne (1835–1908), English clergyman and cricketerFrederick J. Horne (1880–1959), a four-star admiral in the United States NavyHenry Horne, 1st Baron Horne (1861–1929), British generalJames A. Horne, British sleep scientist and co-developer of the Morningness–eveningness questionnaireJames H. Horne (1874–1959), American college sports coachJames W. Horne (1881–1942), American actor, screenwriter, and film directorJames Welton Horne (1853–1922), Canadian land developer, businessman, and political figureJim Horne (model) (1917–2008), American modelJohn Horne (1848–1928), British geologistJohn Horne (botanist) (1835–1905), British botanistKeith Horne (born 1971), South African golferKenneth Horne (1907–1969), English comedian and businessmanKenneth Horne (writer) (1900–1975), English writer and playwrightLena Horne (1917–2010), American singer, actress and civil rights activistMarilyn Horne (born 1934), American opera singerMathew Horne (born 1978), British actor and comedianMatt Horne (born 1970), New Zealand cricketerRichard Henry Horne (1803–1884), English poetThomas Horne (disambiguation), various peopleWillie Horne (1922–2001), British rugby league player