Hopley is an English surname. Notable people with the surname include:
Damian Hopley (born 1970), English former rugby union player
Edward Hopley (1816–1869), English painter
Hannes Hopley (born 1981), South African discus thrower
Frederick John Vanderbyl Hopley, (1883-1951), South African sportsman
Lizzie Hopley (also known as Elizabeth Hopley), British actress and writer
Mark Hopley (born 1984), English rugby union player
Thomas Hopley, a principal in the Eastbourne manslaughter, an 1860 legal case in England
