Hooft or 't Hooft is a Dutch surname. Notable people with the surname include:
Cornelis Hooft (1547–1627), Dutch statesmanPieter Corneliszoon Hooft (1581–1647), Dutch historian, poet and playwrightCatharina Hooft (1618–1691), woman of the Dutch Golden AgeWillem Visser 't Hooft (1900–1985), Dutch theologian and the first secretary general of the World Council of ChurchesHaas Visser 't Hooft (1905–1977), Dutch field hockey playerFrancis van 't Hooft (born 1940), Dutch field hockey playerGerard 't Hooft (born 1946), Dutch theoretical physicist9491 Thooft (without an apostrophe) is an asteroid named after Gerard 't HooftJotie T'Hooft (1956–1977), Flemish Belgian neo-romantic poet