Hoffmeister is a German surname. Notable people with the surname include:
Bert Hoffmeister (1907–1999), Canadian Army officer, businessman, and conservationist
Cuno Hoffmeister (1892–1968), German astronomer and geophysicist, founder of Sonneberg Observatory
Edmund Hoffmeister (1893–1951), German, Army officer, Generalleutnant
Frank Hoffmeister (born 1965), German backstroke swimmer
Franz Hoffmeister (1898–1943), Roman Catholic priest
Franz Anton Hoffmeister (1754–1812), German composer and music publisher
Freya Hoffmeister (born 1964), German expeditioner and sea-kayaker
Gunhild Hoffmeister (born 1944), East German-German female middle distance runner
Jesse Hoffmeister (1872–1933), Major League Baseball player
