Hessler is a surname. Notable people with the surname include:
Alexander Hessler (1823-1895), American photographerGeorg Hessler (1427–1482), German Roman Catholic cardinal and bishopGerd Hessler (born 1948), German cross country skierGordon Hessler (1925–2014), British film and television directorHans-Joachim Hessler (born 1968), German composer, musician and musicologistPeter Hessler (born 1969), American writer and journalistRowe Hessler (born 1991), American speedcuberVanessa Hessler (born 1988), American-Italian model and actress