Hernando de Manrique de Rojas

Hernando de Manrique de Rojas was a Spanish colonial governor of the Colony of Santiago (Jamaica) c.1575.

In late 1562 he commanded Spanish forces sent to destroy Charlesfort, a French fort at Port Royal, South Carolina. This fort had been abandoned after its leader Jean Ribault had returned to France to obtain supplies and had been delayed there by the outbreak of another phase of the French Wars of Religion. The Spanish, however, wanted to make it harder for the French to return.

Manrique de Rojas also explored the coasts of what is today the Eastern United States.