Hephaestion is a genus of beetles in the family Cerambycidae, containing the following species:
Hephaestion annulatum Philippi, 1859
Hephaestion auratum Cerda, 1968
Hephaestion bullocki Cerda, 1968
Hephaestion chalybeum Philippi, 1865
Hephaestion corralensis Philippi & Philippi, 1864
Hephaestion cyanopterum Philippi & Philippi, 1864
Hephaestion flavicornis Philippi & Philippi, 1864
Hephaestion fuscescens Philippi & Philippi, 1864
Hephaestion holomelas Philippi & Philippi, 1864
Hephaestion lariosi Bosq, 1951
Hephaestion nigricornis Fairmaire & Germain, 1861
Hephaestion ocreatum Newman, 1840
Hephaestion pallidicornis Fairmaire & Germain, 1859
Hephaestion tolhuaca Cerda, 1995
Hephaestion versicolor Philippi, 1859
Hephaestion violaceipennis Fairmaire & Germain, 1861