Hentschel is a Germanic surname. People with this surname include:
David Hentschel, English recording engineer, writer and music producer
Erwin Hentschel (1917–1944), German Knight's Cross recipient
Franziska Hentschel (born 1970), German field hockey player
Johannes Hentschel (1908–1982), German-Danish master electro-mechanic
Trent Hentschel (born 1982), Australian rules footballer
York Hentschel (born 1953), Canadian footballer