Henry Henderson Institute (HHI) is an educational establishment in Blantyre, Malawi, founded in 1909. It was named in honour of Henry Henderson (1843-91), lay missionary of the Church of Scotland, who founded the Blantyre Mission.
The original foundation included a primary school, a teacher training college, a theological college, and a technical college to teach practical skills such as carpentry, bricklaying and printing. It also served as printer for the Blantyre Mission; producing religious texts, school textbooks, and government and other daily and weekly publications. Later, training in mechanical skills was added to the curriculum. In the late 1950s, a secondary school was opened.
HHI is said to have "played a most significant role in religious, educational, and political developments in Malawi".
The Institute now lies within the grounds of St Michael and All Angels Church, Blantyre.