Helcystogramma pantheropa is a moth in the Gelechiidae family. It was described by Meyrick in 1913. It is found in South Africa.
The wingspan is 12–13 mm. The forewings are dark ashy-fuscous, slightly whitish-sprinkled with a slight pale ochreous dash beneath the costa near the base and a pale yellow-ochreous transverse blotch representing the plical and first discal stigmata, reaching the dorsum, more or less brownish-suffused except on the margins. There is also a blackish or dark brown spot representing the second discal, sometimes edged with pale yellow-ochreous, as well as a triangular suffused pale yellow-ochreous spot on the costa at three-fourths, where a very fine indistinct angulated line of pale ochreous scales runs to the tornus. The hindwings are dark grey.