Heisler is a surname. Notable people with the surname include:
Charles L. Heisler, American steam locomotive designer
Conrad Heisler, character in The Angry Hills (film)
Gregory Heisler (born 1954), American photographer
Jindřich Heisler, a Czech surrealist poet, friend of Toyen
L. Heisler Ball (1861–1932), physician and Delaware Senator
Mark Heisler, a sports writers and author
Marcy Heisler (born 1967), musical theater writer and performer
Mike Heisler, American comic book writer
Todd Heisler (born 1972), American photojournalist
Randy Heisler (born 1961), American Olympic discus thrower
Stuart Heisler (1896–1979), film and television director
