Hartwell is a surname. Notable people with the surname include:
Lord Hartwell, proprietor of The Daily Telegraph, mid-20th C
Abraham Hartwell (1553–1606), English translator and antiquarian
Alfred S. Hartwell (1836–1912), American Civil War officer and Hawaii judge
Ambrose Hartwell (1883–??), English footballer
Calvin Hartwell (died 1920), Mayor of Pasadena, California (1896–98)
Charles Hartwell (1825–1905), American missionary
Charles Leonard Hartwell (1873–1951), British sculptor
David G. Hartwell (1941–2016), American science fiction and fantasy editor
Edgerton Hartwell (born 1978), former American footballer
Josh Hartwell (1869–1940), 19th-century American college football coach
Leland H. Hartwell (born 1939), President and director of the Fred Hutchinson Cancer Research Center, Seattle; 2001 Nobel Prize laureate
Lori Hartwell, Founder and president of the Renal Support Network
Martin Hartwell, Canadian bush pilot
William Hartwell (1880–??), English footballer
Fictional characters:
Harley Hartwell, character from the manga series Case Closed