Hartnell is an English surname. Notable people with this surname include the following:
Andy Hartnell, American comic book writer
Bryan Calvin Hartnell, victim of the Zodiac Killer in California, 1969
Sir Norman Hartnell (1901–1979), English fashion designer
Scott Hartnell (born 1982), Canadian professional ice hockey player
Tim Hartnell (1951–1991), an Australian journalist
William Hartnell (1908–1975), English actor who portrayed the First Doctor in the BBC's Doctor Who
William Edward Petty Hartnell otherwise Don Guillermo Arnel (1798–1854), English-born merchant and administrator in California
