Hardison is a surname. Notable people with the surname include:
Benjamin Hardison (1761–1823), farmer, miller and political figure in Upper Canada
Casey William Hardison (born 1971), American chemist
Dee Hardison (born 1956), former American football defensive lineman in the National Football League
Kadeem Hardison (born 1965), American actor
Marcus Hardison (born 1992), American football player
Wallace Hardison (1850–1909), one of the founders of Union Oil
Ross Hardison, American biochemist and scientist
Fictional characters:
Alec Hardison, a fictional hacker from the TV series Leverage
