Hampel is a surname. Notable people with the surname include:
Anton Joseph Hampel (1710–1771), German classical horn playerDesiderius Hampel (1895–1981), Croatian SS generalFelicity Hampel (born 1955), Australian lawyer and judgeGeorge Hampel (disambiguation), multiple peopleGunter Hampel (born 1937), German musician and composerJarosław Hampel (born 1982), Polish motorcycle speedway riderJózsef Hampel (1849–1913), Hungarian archaeologistOlaf Hampel (born 1965), German bobsledderOliver Hampel (born 1985), German footballerOtto and Elise Hampel (died 1943), German activistsPaul William Hampel, Russian spy