Hamby is a surname. Notable people with the surname include:
Anthony Freskyn Charles Hamby Chaplin, 3rd Viscount Chaplin (1906–1981), amateur zoologist and musician
Barbara Hamby (born 1952), American poet, fiction writer, editor and critic
Jeannette Hamby (born 1933), American politician and nurse
Jessica Hamby, fictional character in the True Blood series
Jim Hamby (1897–1991), American baseball player
Priscilla Hamby (born 1982), American illustrator and comic book artist