PubChem CID 11370880 Formula C21H28O3 Molar mass 328.445 g/mol | ChemSpider 9545797 3D model (Jmol) Interactive image | |
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HU-336 is a strongly antiangiogenic compound, significantly inhibiting angiogenesis at concentrations as low as 300 nM. It inhibits angiogenesis by directly inducing apoptosis of vascular endothelial cells without changing the expression of pro- and antiangiogenic cytokines and their receptors. HU-336 is highly effective against tumor xenografts in nude mice.
References
HU-336 Wikipedia(Text) CC BY-SA