Samiksha Jaiswal

HTN3

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Species  Human
Entrez  3347
Human  Mouse
Ensembl  n/a
HTN3
Aliases  HTN3, HIS2, HTN2, HTN5, histatin 3
External IDs  HomoloGene: 133553 GeneCards: HTN3

Histatin 3, also known as HTN3, is a protein which in humans is encoded by the HTN3 gene.

Function

The primary protein encoded by HTN3 is histatin 3. Histatins are a family of small, histidine-rich, salivary proteins, encoded by at least two loci (HTN3 and HTN1). Post-translational proteolytic processing results in many histatins: e.g., histatins 4-6 are derived from histatin 3 by proteolysis. Histatins 1 and 3 are primary products of HIS1(1) and HIS2(1) alleles, respectively. Histatins are believed to have important non-immunological, anti-microbial function in the oral cavity. Histatin 1 and histatin 2 are major wound-closing factors in human saliva.

References

HTN3 Wikipedia


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