Species Human Entrez 3213 | Human Mouse Ensembl ENSG00000120093 | |
Aliases HOXB3, HOX2, HOX2G, Hox-2.7, homeobox B3 External IDs MGI: 96184 HomoloGene: 1617 GeneCards: HOXB3 |
Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene.
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML).
References
HOXB3 Wikipedia(Text) CC BY-SA