Trisha Shetty

HOXA7

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Species  Human
Entrez  3204
Human  Mouse
Ensembl  ENSG00000122592
HOXA7
Aliases  HOXA7, ANTP, HOX1, HOX1.1, HOX1A, homeobox A7
External IDs  MGI: 96179 HomoloGene: 56001 GeneCards: HOXA7

Homeobox protein Hox-A7 is a protein that in humans is encoded by the HOXA7 gene.

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila.

References

HOXA7 Wikipedia


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