Species Human Entrez 92906 | Human Mouse Ensembl ENSG00000143889 | |
Aliases HNRNPLL, HNRPLL, SRRF, heterogeneous nuclear ribonucleoprotein L like External IDs MGI: 1919942 HomoloGene: 26701 GeneCards: HNRNPLL | ||
Heterogeneous nuclear ribonucleoprotein L-like is a protein that in humans is encoded by the HNRNPLL gene.
Function
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008].
References
HNRNPLL Wikipedia(Text) CC BY-SA