HMS Esk may refer to one of the following Royal Navy ships named Esk after a Celtic word meaning a river:
HMS Esk (1813), a 20-gun post ship launched in 1813. She was sold in 1829.
HMS Esk (1854), a wood screw corvette launched in 1854. She was broken up in 1870.
HMS Esk (1877), an iron screw gunboat launched in 1877. She was sold in 1903.
HMS Esk (1905), a tender transferred from the War Department in 1905. She was sold in 1920.
HMS Esk (1934), an E class destroyer launched in 1934. She was sunk by a mine in 1940 north west of Texel.