Entrez 3163 | Ensembl n/a | |
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External IDs MGI: 109373 HomoloGene: 1611 GeneCards: HMOX2 |
Function
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 (this enzyme) belong to the heme oxygenase family.
References
HMOX2 Wikipedia(Text) CC BY-SA