Suvarna Garge

HMOX2

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Species  Human
Entrez  3163
Human  Mouse
Ensembl  n/a
HMOX2
Aliases  HMOX2, HO-2, heme oxygenase 2
External IDs  MGI: 109373 HomoloGene: 1611 GeneCards: HMOX2

Heme oxygenase 2 is an enzyme that in humans is encoded by the HMOX2 gene.

Function

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 (this enzyme) belong to the heme oxygenase family.

References

HMOX2 Wikipedia


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