Entrez 3118 | Ensembl n/a | |
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Aliases HLA-DQA2, DX-ALPHA, HLA-DXA, HLA-DQA2, HLA-DQA2 (gene), major histocompatibility complex, class II, DQ alpha 2 External IDs HomoloGene: 134076 GeneCards: HLA-DQA2 | ||
HLA class II histocompatibility antigen, DQ(6) alpha chain is a protein that in humans is encoded by the HLA-DQA2 gene. Also known as HLA-DXA or DAAP-381D23.2, it is part of the human leucocyte antigen system.
The protein encoded by this gene is expressed, but unlike HLA-DQA1, it apparently unable to heterodimerize with HLA class II beta chain paralogues. The low level of HLA-DQA2 expression is apparently due to impaired transcription factor binding to the HLA-DQA2 gene promoter.
References
HLA-DQA2 Wikipedia(Text) CC BY-SA