Puneet Varma (Editor)

HLA DQA2

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Covid-19
Species  Human
Entrez  3118
Human  Mouse
Ensembl  n/a
HLA-DQA2
Aliases  HLA-DQA2, DX-ALPHA, HLA-DXA, HLA-DQA2, HLA-DQA2 (gene), major histocompatibility complex, class II, DQ alpha 2
External IDs  HomoloGene: 134076 GeneCards: HLA-DQA2

HLA class II histocompatibility antigen, DQ(6) alpha chain is a protein that in humans is encoded by the HLA-DQA2 gene. Also known as HLA-DXA or DAAP-381D23.2, it is part of the human leucocyte antigen system.

The protein encoded by this gene is expressed, but unlike HLA-DQA1, it apparently unable to heterodimerize with HLA class II beta chain paralogues. The low level of HLA-DQA2 expression is apparently due to impaired transcription factor binding to the HLA-DQA2 gene promoter.

References

HLA-DQA2 Wikipedia


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