Structure αβ heterodimer Subtype allele | Older names AX"BG" allele Available structures | |
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Subunits HLA-A*8001, β2-microglobulin | ||
HLA-A80 (A80) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α80 subset of HLA-A α-chains. For A80, the alpha "A" chain are encoded by the HLA-A*80 allele group and the β-chain are encoded by B2M locus. This group currently is dominated by A*8001. A80 and A*80 are almost synonymous in meaning.
A80 is more common in West Central Africa. A80 is the least common HLA-A allele group.
Serotype
A80 HLA-A80 typing is poor. Most typing is done with SSP-PCR. Most of 8001 are detected with "Blank" serotype..
References
HLA-A80 Wikipedia(Text) CC BY-SA